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Accession IconGSE63664

Gene expression induced by DOT1L and Menin inhibition in cell line models of leukemia

Organism Icon Homo sapiens, Mus musculus
Sample Icon 56 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2), Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

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Description
Gene expression upon DOT1L inhibition, or Menin inhibition, or a combination of DOT1L and Menin inhibiting agents, was assessed in several MLL-rearranged human cell lines and a mouse model of MLL-AF9 leukemia.
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56
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Cell line
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