Induction of ER stress in HCT116 colon cancer cells

GSE63252

Homo sapiens

27 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

To investigate the role of p53 and DICER in the induction of ER stress, wildtype, p53 knockout or DICER mutant HCT116 colon cancer cells were treated with the ER stress inducers tunicamycin or brefeldin A for 24 hours.

PubMed ID

25475719

Publication Title

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

Total Samples

Submitter’s Institution

National University of Ireland Galway

Authors

Deegan S, Koryga I, Glynn SA, Gupta S, Gorman AM, Samali A

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-63252

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