Transcriptomic profiles of skin fibroblasts from patients affected by schizophrenia and controls

Whole-genome expression studies in peripheral tissues of patients affected by schizophrenia (SCZ) can provide new insights into the molecular basis of the disorder and innovative biomarkers that may be of great usefulness in the clinical practice. Recent evidence suggests that skin fibroblasts could represent a non-neural peripheral model useful to investigate molecular alterations in psychiatric disorders.

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Cattane N, Minelli A, Milanesi E, Maj C, Bignotti S, Bortolomasi M, Bocchio Chiavetto L, Gennarelli M