Microarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs

GSE61582

Mus musculus

2 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

ShhCre;Mst1/2flx/flx (Mst1/2 D/D) mice were generated to conditionally delete Mst1 and Mst2 from epithelial progenitors during lung morphogenesis. Lungs from E18.5 control and Mst1/2 D/D mice were mechanically and enzymatically dissociated to generate single cell suspension. Epcam(+) cells were isolated using magnetic microbeads.

PubMed ID

25480985

Publication Title

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.

Total Samples

Submitter’s Institution

Cincinnati Children's Hospital Reseach Foundation

Authors

Lange AW, Sridharan A, Xu Y, Stripp BR, Perl AK, Whitsett JA

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-61582

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