AKT pathway genes define 5 prognostic subgroups in glioblastoma

GSE61335

Homo sapiens

124 Downloadable Samples

Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

GBM samples were clusered using gene expression of AKT pathway genes to reveal at least 5 GBM AKT subtypes, having distinct DNA copy number alterations, enrichment in oncogenes and tumor suppressor genes and patterns of expression for PI3K/AKT/mTOR signaling components.

PubMed ID

24984002

Publication Title

AKT pathway genes define 5 prognostic subgroups in glioblastoma.

Total Samples

124

Submitter’s Institution

UCSF

Authors

Joy A, Ramesh A, Smirnov I, Reiser M, Misra A, Shapiro WR, Mills GB, Kim S, Feuerstein BG

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-61335

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