Expression data of neural progenitor cells differentiation from human embryonic stem cells

GSE61050

Homo sapiens

5 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Mocetinostat (MGCD) which is a kind of histone deacetylase inhibitors (HDACi) promotes human embryonic stem cells (hESCs) differentiation towards neural progenitor cells (NPCs). Application of HDAC inhibitors (HDACi) increased the expression of neuroectodermal markers once neural differentiation was initiated, thereby leading to more NPC generation.

PubMed ID

25406762

Publication Title

Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells.

Total Samples

Submitter’s Institution

Institute of Health Sciences

Authors

Yang J, Tang Y, Liu H, Guo F, Ni J, Le W

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-61050

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