Gene expression changes between sensitive and YK-4-279-resistant Ewing's Sarcoma cell lines

GSE61042

Homo sapiens

18 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

Microarray gene expression analysis conducted from cell lines in each of three cohorts: (1) Resistant ES cell lines, (2) Sensitive parental ES cell lines treated with YK-4-279 for 72 hours, and (3) untreated sensitive parental ES cell lines (Three replicates from TC32 & TC71 original parental cell lines)

PubMed ID

25964201

Publication Title

An Oral Formulation of YK-4-279: Preclinical Efficacy and Acquired Resistance Patterns in Ewing Sarcoma.

Total Samples

Submitter’s Institution

UT-MD-Anderson Cancer Center

Authors

Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Aiyer RA, Maywald RL, Buford AS, Doolittle DK, Culotta KS, O'Dorisio JE, Ludwig JA

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-61042

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