Gene expression data of Kas-/- mouse emobryonic fibroblasts transfected with KRAS siRNAs

GSE59823

Mus musculus

29 Downloadable Samples

Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Submitter Supplied Information

Description

We used Kras/Hras/Nras-triple knockout MEFs expressing recombinant Nras to test the off-target effect of 2 Kras siRNAs at different transfection concentrations.

PubMed ID

25100204

Publication Title

Development of siRNA payloads to target KRAS-mutant cancer.

Total Samples

Submitter’s Institution

National Cancer Institute

Authors

Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-59823

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