Transcriptional signature of Th17 cells expressing ICOS-based CARs

GSE58867

Homo sapiens

43 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

Analysis of TH17 cells redirected with chimeric antigen receptors (CAR) expressing various signaling domains (including CD28, 4-1BB and ICOS) after surrogate antigen stimulation.

PubMed ID

24986688

Publication Title

ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells.

Total Samples

Submitter’s Institution

University of Pennsylvania

Authors

Guedan S, Chen X, Madar A, Carpenito C, McGettigan SE, Frigault MJ, Lee J, Posey AD Jr, Scholler J, Scholler N, Bonneau R, June CH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-58867

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