First ruxolitinib treatment of human alopecia areata patients

GSE58573

Homo sapiens

7 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Two patients with alopecia areata were treated with systemic ruxolitinib. Skin biopsies were taken before starting treatment and 12 weeks after starting treatment.

PubMed ID

25129481

Publication Title

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.

Total Samples

Submitter’s Institution

Columbia University

Authors

Xing L, Dai Z, Jabbari A, Cerise JE, Higgins CA, Gong W, de Jong A, Harel S, DeStefano GM, Rothman L, Singh P, Petukhova L, Mackay-Wiggan J, Christiano AM, Clynes R

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-58573

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