Gene expression signature associated with BRAFV600E mutation based on transgenic mouse model (mouse)

GSE58546

Mus musculus

9 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

BRAFV600E mutation is the most frequent molecular event in papillary thyroid carcinoma. The relation of this genetic alteration with the factors od poor prognosis has been reported as well as its influence on PTC gene signature. However human material disables distinction of cancer causes from its effect.

PubMed ID

26625260

Publication Title

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma.

Total Samples

Submitter’s Institution

University of Warsaw

Authors

Rusinek D, Swierniak M, Chmielik E, Kowal M, Kowalska M, Cyplinska R, Czarniecka A, Piglowski W, Korfanty J, Chekan M, Krajewska J, Szpak-Ulczok S, Jarzab M, Widlak W, Jarzab B

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-58546

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