Expression data from liver of Retnla transgenic (Tg) and non-transgenic (non-Tg) mice.

We found that Retnla-Tg mice had significantly lower serum cholesterol levels than non-Tg mice on a high-fat diet (HFD). To explore the molecular mechanisms underlying the cholesterol-lowering effects of Retnla under hyperlipidemic conditions, we subjected age- and sex-matched Retnla-Tg and non-Tg mice to a HFD for 4 weeks.

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Lee MR, Lim CJ, Lee YH, Park JG, Sonn SK, Lee MN, Jung IH, Jeong SJ, Jeon S, Lee M, Oh KS, Yang Y, Kim JB, Choi HS, Jeong W, Jeong TS, Yoon WK, Kim HC, Choi JH, Oh GT