Altered mRNA expression profile of GW4064 treated mouse livers compared to vehicle control

GSE57305

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Submitter Supplied Information

Description

Farnesoid X receptor (FXR) is a ligand activated nuclear receptor belonging to the nuclear receptor superfamily. Bile acids (BAs) are the endogenous ligand for FXR. FXR is a master regulator of BA homestasis, including BA synthesis, metabolism, transport, and enterohepatic circulation of BAs. Besides, FXR is involved in regulating diverse physioligical function in both humans and mice.

PubMed ID

25198545

Publication Title

Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes.

Total Samples

Submitter’s Institution

Rutgers University

Authors

Zhan L, Liu HX, Fang Y, Kong B, He Y, Zhong XB, Fang J, Wan YJ, Guo GL

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-57305

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