In Vitro Transformation of Primary Human CD34+ Cells by AML Fusion Oncogenes: Early Gene Expression Profiling Reveals Possible Drug Target in AML

GSE57194

Homo sapiens

29 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Different fusion oncogenes in acute myeloid leukemia (AML) have distinct clinical and laboratory features suggesting different modes of malignant transformation. Here we compare the in vitro effects of representatives of major groups of AML fusion oncogenes on primary human CD34+ cells.

PubMed ID

20805992

Publication Title

In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML.

Total Samples

Submitter’s Institution

Washington University in Saint louis

Authors

Abdul-Nabi AM, Yassin ER, Varghese N, Deshmukh H, Yaseen NR

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-57194

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