Function of LIM-only protein FHL2 in vascular smooth muscle cells

GSE56860

Mus musculus

6 Downloadable Samples

Illumina MouseWG-6 v2.0 expression beadchip

Submitter Supplied Information

Description

The LIM-only protein FHL2 is expressed in SMCs and inhibits SMC-rich lesion formation. However, the underlying mechanism behind FHL2's action in SMCs has been only partially resolved. To further elucidate the role of FHL2 in SMCs we compared the transcriptome of cultured SMCs derived from wild-type (WT) and FHL2-knockout (KO) mice.

PubMed ID

25332231

Publication Title

LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis.

Total Samples

Submitter’s Institution

Academic Medical Center

Authors

Kurakula K, Sommer D, Sokolovic M, Moerland PD, Scheij S, van Loenen PB, Koenis DS, Zelcer N, van Tiel CM, de Vries CJ

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-56860

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