Expression data from yeast wild type (WT) and sod1 strains after treatment with hydrogen peroxide (H2O2)

GSE55081

Saccharomyces cerevisiae

4 Downloadable Samples

Affymetrix Yeast Genome 2.0 Array (yeast2)

Submitter Supplied Information

Description

An important cellular defense mechanism against oxidative stress is the induction of genes involved in ROS resistance and DNA damage repair. Under normal conditions, Sod1 is localized mainly in the cytosol. However, we found that Sod1 translocates into the nucleus after oxidative stress.

PubMed ID

24647101

Publication Title

Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance.

Total Samples

Submitter’s Institution

Rutgers Cancer Institute of New Jersey

Authors

Tsang CK, Liu Y, Thomas J, Zhang Y, Zheng XF

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-55081

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