TRIBAL overexpression in HepG2 cells

GSE54937

Homo sapiens

5 Downloadable Samples

Affymetrix Human Transcriptome Array 2.0 (hta20), Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version)

Submitter Supplied Information

Description

Objective - The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease (CAD) in humans. The lipid associated SNPs identified by genome-wide association studies (GWAS) are located ~ 30 kb downstream from TRIB1 suggesting complex regulatory effects on genes or pathways relevant to hepatic triglyceride metabolism. The goal of this study was to investigate the functional relationship between common SNPs at the TRIB1 locus and plasma lipid traits.

PubMed ID

24895164

Publication Title

Functional analysis of the TRIB1 associated locus linked to plasma triglycerides and coronary artery disease.

Total Samples

Submitter’s Institution

University of Ottawa Heart Institute

Authors

Douvris A, Soubeyrand S, Naing T, Martinuk A, Nikpay M, Williams A, Buick J, Yauk C, McPherson R

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-54937

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