Predicting Features of Breast Cancer with Gene Expression Patterns

Predictors built from gene expression data accurately predict ER, PR, and HER2 status, and divide tumor grade into high-grade and low-grade clusters; intermediate-grade tumors are not a unique group. In contrast, gene expression data cannot be used to predict tumor size or lymphatic-vascular invasion.

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Lu X, Lu X, Wang ZC, Iglehart JD, Zhang X, Richardson AL