PU.1 promotes cell cycle exit in the murine myeloid lineage associated with down-regulation of E2F1

A doxycycline-inducible system was used to induce PU.1 expression in cultured myeloid cell lines. The parent cell line used was BN (Kamath et al., Leukemia 22:1214-1225, 2008).

6

Ziliotto R, Gruca MR, Podder S, Noel G, Ogle CK, Hess DA, DeKoter RP