Loss of BMPR2 Signaling in Smooth Muscle in Mouse Lung

Mice expressing a doxycycline-inducible dominant negative BMPR2 transgene expressed only in smooth muscle are activated for one or eight weeks, and compared to transactivator-only mice also fed doxycycline. All mice are 12 weeks of old at sacrifice.

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Tada Y, Majka S, Carr M, Harral J, Crona D, Kuriyama T, West J