The effect of imatinib therapy on tumor associated macrophages (TAMs) in human gastrointestinal stromal tumor (GIST)

GSE51697

Homo sapiens

20 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

The gene expression profile of TAMs microbead isolated from freshly obtained human GISTs were compared in tumors that were untreated, responding to imatinib (sensitive), or resistant to imatinib (resistant)

PubMed ID

24323358

Publication Title

KIT oncogene inhibition drives intratumoral macrophage M2 polarization.

Total Samples

Submitter’s Institution

Memorial Sloan Kettering Cancer Center

Authors

Cavnar MJ, Zeng S, Kim TS, Sorenson EC, Ocuin LM, Balachandran VP, Seifert AM, Greer JB, Popow R, Crawley MH, Cohen NA, Green BL, Rossi F, Besmer P, Antonescu CR, DeMatteo RP

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-51697

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