Expression data from rhesus macaque colon, jejunum, and lung

GSE51615

Macaca mulatta

32 Downloadable Samples

Affymetrix Rhesus Macaque Genome Array (rhesus)

Submitter Supplied Information

Description

The mucosa that lines the respiratory and gastrointestinal (GI) tracts is an important portal of entry for pathogens and provides the frontline of immune defense against HIV infection. Using the simian immunodeficiency virus (SIV) rhesus macaque model, we have performed a comparative analysis of host gene expression in the lung and GI mucosa in response to SIV infection and antiretroviral therapy.

PubMed ID

24610016

Publication Title

Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection.

Total Samples

Submitter’s Institution

University of California, Davis

Authors

Verhoeven D, George MD, Hu W, Dang AT, Smit-McBride Z, Reay E, Macal M, Fenton A, Sankaran-Walters S, Dandekar S

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-51615

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