Gene expression analysis of RB1 knockdown in bone in response to radiation

GSE50532

Homo sapiens

36 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

The role of RB1 in response to radiation was examined in human osteoblasts. We demonstrate that RB1 induced SASP genes, a response which was attenuated in RB1 knockdown osteoblasts.

PubMed ID

24231354

Publication Title

Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.

Total Samples

Submitter’s Institution

Peter MacCallum Cancer Centre

Authors

Kansara M, Leong HS, Lin DM, Popkiss S, Pang P, Garsed DW, Walkley CR, Cullinane C, Ellul J, Haynes NM, Hicks R, Kuijjer ML, Cleton-Jansen AM, Hinds PW, Smyth MJ, Thomas DM

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-50532

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