Expression data from Saccharomyces cerevisae strains deleted for the RNA-binding hnRNP Npl3

GSE50186

Saccharomyces cerevisiae

6 Downloadable Samples

Affymetrix Yeast Genome 2.0 Array (yeast2)

Submitter Supplied Information

Description

Transcription is a major obstacle for replication fork progression and a cause of genome instability. Such instability increases in mutants with a suboptimal assembly of the nascent messenger ribonucleo-protein particle (mRNP), as THO/TREX and some heterogeneous nuclear ribonucleoproteins (hnRNPs) mutants.

PubMed ID

24240235

Publication Title

The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability.

Total Samples

Submitter’s Institution

CABIMER, Universidad de Sevilla-CSIC

Authors

Santos-Pereira JM, Herrero AB, García-Rubio ML, Marín A, Moreno S, Aguilera A

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-50186

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