Gene expression in the blood of Live Attenuated Rev-Independent NefSIV infected Rhesus macaques during acute infection

GSE49663

Macaca mulatta

6 Downloadable Samples

Affymetrix Rhesus Macaque Genome Array (rhesus)

Submitter Supplied Information

Description

Rhesus macaques (RMs) inoculated with live-attenuated Rev-Independent Nef simian immunodeficiency virus (Rev-Ind NefSIV) as adults or neonates controlled viremia to undetectable levels and showed no signs of immunodeficiency over 6-8 years of follow-up. We tested the capacity of this live-attenuated virus to protect RMs against pathogenic, heterologous SIVsmE660 challenges

PubMed ID

24098702

Publication Title

Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques.

Total Samples

Submitter’s Institution

Emory Univeristy

Authors

Byrareddy SN, Ayash-Rashkovsky M, Kramer VG, Lee SJ, Correll M, Novembre FJ, Villinger F, Johnson WE, von Gegerfelt A, Felber BK, Ruprecht RM

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-49663

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