Gene expression on in vitro activated DCs

GSE49328

Mus musculus

2 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

We have analyzed the effects of IL-27 signaling in dendritic cells (DCs) in the activation and polarization of effector and regulatory T cells, and the development of experimental autoimmune encephalomyelitis, an experimental model of multiple sclerosis.

PubMed ID

23995234

Publication Title

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.

Total Samples

Submitter’s Institution

Harvard Medical Institute

Authors

Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S, Kuchroo VK, Robson SC, Quintana FJ

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-49328

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