Comparison of RNA-Seq and Microarray in Transcriptome Profiling During T Cell Activation

Samples in this study probe the gene expression kinetics in human CCR6+ Th17 memory T cells activated under Th17 condition. Human CCR6+ Th17 memory T cells were purified from PBMC and gene expression was studied over a time course of 3 days after activation under Th17 condition. RNA from these samples was also profiled using RNA-Seq to compare different transcriptome profiling technologies.

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Zhao S, Fung-Leung WP, Bittner A, Ngo K, Liu X