Expression data from Adipose Stem Cells (ASC) from morbidly obese and non-obese individuals

GSE48964

Homo sapiens

6 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

The adipose tissue is an endocrine regulator and a risk factor for atherosclerosis and cardiovascular disease when by excessive accumulation induces obesity. Although the adipose tissue is also a reservoir for stem cells (ASC) their function and stemcellness has been questioned. Our aim was to investigate the mechanisms by which obesity affects subcutaneous white adipose tissue (WAT) stem cells.

PubMed ID

24040759

Publication Title

Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype.

Total Samples

Submitter’s Institution

Cardiovascular Research Center, CSIC-ICCC

Authors

Oñate B, Vilahur G, Camino-López S, Díez-Caballero A, Ballesta-López C, Ybarra J, Moscatiello F, Herrero J, Badimon L

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-48964

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