Alzheimer's Disease Dataset

GSE48350

Homo sapiens

246 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

This dataset contains microarray data from normal controls (aged 20-99 yrs) and Alzheimer's disease cases, from 4 brain regions: hippocampus, entorhinal cortex, superior frontal cortex, post-central gyrus. Changes in expression of synaptic and immune related genes were analyzed, investigating age-related changes and AD-related changes, and region-specific patterns of change.

PubMed ID

18832152

Publication Title

Gene expression changes in the course of normal brain aging are sexually dimorphic.

Total Samples

253

Submitter’s Institution

UC Irvine

Authors

Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR, Cotman CW

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-48350

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