Comparing gene expression in stem/progenitor cells from patients with CML in chronic, accelerated and blastic phase with normal volunteers

GSE47927

Homo sapiens

67 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

A comparison of global gene expression between rigorously defined stem and progenitor cells from patients with chronic myeloid leukaemia (CML) in chronic (CP), accelerated (AP) and blastic (BC) phase and similar populations isolated from normal volunteers.

PubMed ID

23836560

Publication Title

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.

Total Samples

Submitter’s Institution

University of Glasgow

Authors

Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, Padget M, Irvine DA, Sliwinski T, Haas K, Lee J, Geng H, Roy D, Slupianek A, Rassool FV, Wasik MA, Childers W, Copland M, Müschen M, Civin CI, Skorski T

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-47927

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