Effects of MDMA and Venlafaxine treatment in Dark Agouti rats

GSE47541

Rattus norvegicus

No Downloadable Samples

Illumina Rat Ref-12 v1

Submitter Supplied Information

Description

The aim of this study was to examine the hippocampus, frontal cortex and dorsal raphe of Dark Agouti rats with gene expression arrays (Illumina RatRef bead arrays) looking for possible mechanisms and new candidates contributing to the effects of a single dose of MDMA (15 mg/kg) 3 weeks earlier or venlafaxine (40 mg/kg) administration for 3 weeks continously. We also examined the possible interaction between the single dose MDMA treatment and the continous venlafaxine treatment described above.

PubMed ID

24378229

Publication Title

Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats.

Total Samples

Submitter’s Institution

Semmelweis University

Authors

Petschner P, Tamasi V, Adori C, Kirilly E, Ando RD, Tothfalusi L, Bagdy G

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-47541

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