Expression profile for overproduction of DosP

Persister cells are a sub-population of all bacterial cultures which exhibit a non-inheritable, multi-drug tolerance when subjected to lethal antibiotic challenge. These persisters arise as a result of metabolic dormancy, and can resume growth subsequent to antibiotic challenge, leading to recalcitrance of bacterial infections.

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Kwan BW, Osbourne DO, Hu Y, Benedik MJ, Wood TK