Expression data from MDA-MB-231 cells treated with vehicle or YW3-56

GSE46590

Homo sapiens

6 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

PAD4 is overexpressed in many cancer cells. We developed PAD inhibitors that efficiently inhibit the cancer cell growth. One inhibitor YW3-56 could efficently induce cell death of triple negative breast cancer MDA-MB-231 cells.

PubMed ID

25612620

Publication Title

ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells.

Total Samples

Submitter’s Institution

The Penn State University

Authors

Wang S, Chen XA, Hu J, Jiang JK, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-46590

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