Examination of the MAPK pathway gene expression in patient samples

GSE45405

Homo sapiens

21 Downloadable Samples

Illumina humanRef-8 v2.0 expression beadchip

Submitter Supplied Information

Description

Microarray analysis of total RNA isolated from samples of circulating tumor cells from 7 patients before romidepsin infusion (0 hours), at 4 h after initiation of the infusion (4 hours) and 24 h after initiation of the infusion (24 hours).

PubMed ID

23532732

Publication Title

MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor.

Total Samples

Submitter’s Institution

The Wistar Institute

Authors

Chakraborty AR, Robey RW, Luchenko VL, Zhan Z, Piekarz RL, Gillet JP, Kossenkov AV, Wilkerson J, Showe LC, Gottesman MM, Collie NL, Bates SE

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-45405

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