In vivo gene expression analysis of C elegans in response to rifampicin

GSE45292

Caenorhabditis elegans

4 Downloadable Samples

Affymetrix C. elegans Genome Array (celegans)

Submitter Supplied Information

Description

We have discovered rifampicin as a glycation inhibitor, which increases life span in C elegans. In order to understand the mechanism of rifampicin action, microarray analysis was performed to study the changes in gene expression brought about by the drug.

PubMed ID

25720500

Publication Title

Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans.

Total Samples

Submitter’s Institution

National Institute of Immunology

Authors

Golegaonkar S, Tabrez SS, Pandit A, Sethurathinam S, Jagadeeshaprasad MG, Bansode S, Sampathkumar SG, Kulkarni MJ, Mukhopadhyay A

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-45292

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