Testing rescue of AR signaling by ectopic expression of mutant AR allele in the presence of MDV-3100 - refine.bio

GSE44924

Homo sapiens

13 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Genetically engineered LNCaPs overexpressing various AR alleles were treated with 0.1% DMSO or 10uM MDV3100 for 24h prior to collection

PubMed ID

Publication Title

An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).

Total Samples

16

Submitter’s Institution

Authors

Korpal M, Korn JM, Gao X, Rakiec DP, Ruddy DA, Doshi S, Yuan J, Kovats SG, Kim S, Cooke VG, Monahan JE, Stegmeier F, Roberts TM, Sellers WR, Zhou W, Zhu P

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

No rows found

Loading...