Expression data from WT and E2A-deficient murine DN2 cells

The E2A transcription factors promote the development of thymus-seeding cells but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. By examining E2A-dependent genes in developing T cells, we will address whether these proteins are involved in these processes.

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Xu W, Carr T, Ramirez K, McGregor S, Sigvardsson M, Kee BL