Analysis of transcripts in PNA-A(15) oligo treated human HEK-293 cells

Mononucleotide A and T repeats are abundant in human genome. Many of A repeats are bound by Argonaute proteins (AGOs). To evaluate the role of AGOs and A repeats in gene regulation, HEK293 cells were treated with 8-amino-3,6-dioxaoctanoic acid added peptide nucleic acid (PNA) AAAAAAAAAAAAAAA oligo (OO-A(15)).

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Aporntewan C, Pin-on P, Chaiyaratana N, Pongpanich M, Boonyaratanakornkit V, Mutirangura A