GSE43061A systems approach identifies progeroid Ercc1[-/] mice as a model system for kidney aging.
Mus musculus
21 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)Submitter Supplied Information
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Using these samples, it has been shown that the transcriptional landscape in glomeruli of Ercc1[-/] mice at a rather young age of 14 weeks mimics that of mice which have undergone real-life renal aging. Thus, young Ercc1[-/] mice can be used as a model system for glomerular aging in future studies.
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