The innate and adaptive immune response to BCG stimulation in splenocytes taken from C57BL/6 mice

The aim of this experiment was to investigate differential gene expression in splenocytes stimulated with BCG from nave and BCG vaccinated mice. The differences between nave and BCG vaccinated mice might indicate the mechanisms by which BCG vaccination confers an enhanced ability of splenocytes from BCG vaccinated mice to inhibit growth of BCG in splenocyte cultures as compared with splenocytes from naive animals.

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Marsay L, Matsumiya M, Tanner R, Poyntz H, Griffiths KL, Stylianou E, Marsh PD, Williams A, Sharpe S, Fletcher H, McShane H