Expression profiling of early lymphoid progenitors deficient for Ebf1 and Foxo1
12 Downloadable Samples
Affymetrix Mouse Genome 430 2.0 Array (mouse4302)
Submitter Supplied Information
Foxo1 and Ebf1 deficiency leads to a similar disruption of normal B-cell development at the level of the common lymphoid progenitor (CLP). Both mouse strains display the existance of LY6D+ CLPs but a marked/complete lack of proB cells.