INTESTINAL FILTER FOR USE IN OESOPHAGEAL CANCER RESEARCH

GSE40220

Homo sapiens

9 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

This study utilise the examination of normal gastro-intestinal tissues to determine a tissue specific signal for use in deriving the intestinal signature of intestinal metaplasias of the oesophagus. Normal oesophageal, colonic and duodenal tissue biopsies were taken after informed consent and RNA was extracted following histological examination of adjacent tissues for normal aperaing mucosa.

PubMed ID

27586588

Publication Title

The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Total Samples

Submitter’s Institution

Institute of Molecular Medicine

Authors

Duggan SP, Behan FM, Kirca M, Zaheer A, McGarrigle SA, Reynolds JV, Vaz GM, Senge MO, Kelleher D

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-40220

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