Tumoral transcriptome profiling of tPTEN-/- mice.

GSE39591

Mus musculus

7 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

tPTEN-/- mice display a deletion of the PTEN tumor suppressor gene specifically in T cells (cross PTEN flox/flox x lck-Cre). They develop T cell lymphoma with a primary thymic tumor and invasion of most organ at late stage of the disease.

PubMed ID

23348702

Publication Title

Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas.

Total Samples

Submitter’s Institution

IPMC/CNRS

Authors

Lounnas N, Rosilio C, Nebout M, Mary D, Griessinger E, Neffati Z, Chiche J, Spits H, Hagenbeek TJ, Asnafi V, Poulsen SA, Supuran CT, Peyron JF, Imbert V

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-39591

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