A novel 3-D organotypic culture model by co-culturing alpha-SMA positive CAF and cholangiocarcinoma cells in a collagen matrix

GSE38889

Rattus norvegicus

13 Downloadable Samples

Affymetrix Rat Genome 230 2.0 Array (rat2302)

Submitter Supplied Information

Description

The increased -smooth muscle-actin positive cancer-associated fibroblastic cells (CAF) in the desmoplastic stroma may relate to a more aggressive cancer and worse survival outcomes for intrahepatic cholangiocarcinoma (ICC) patients

PubMed ID

22568523

Publication Title

Novel organotypic culture model of cholangiocarcinoma progression.

Total Samples

Submitter’s Institution

Virginia Commonwealth University

Authors

Campbell DJ, Dumur CI, Lamour NF, Dewitt JL, Sirica AE

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-38889

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