Expression Data from siRae1 and siNT infected with VSV or mock infected

To test the effect of silencing Rae1 on expression on RNA polymerase II transcripts, host mRNAs were analysed by cDNA microarrays. We hypothesized that if silencing Rae1 expression increases cellular resistance to inhibition of transcription in VSV infected cells, mRNA characteristic of host antiviral response would be increased than compared to cells transfected with control siRNA.

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Rajani KR, Pettit Kneller EL, McKenzie MO, Horita DA, Chou JW, Lyles DS