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Accession IconGSE38215

Expression analysis of control and low protein fed mouse offspring subsequently treated with multiple low doses of STZ

Organism Icon Mus musculus
Sample Icon 10 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

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Description
Low protein (LP) during gestation leads to low birth weight and poor fetal growth, with altered islet development and glucose intolerance in adulthood. Additionally, LP offspring fail to regenerate their -cells following depletion with streptozotocin (STZ), in contrast to control-fed offspring that are capable of -cell regeneration.
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