Dysregulated expression of genes in regulatory T cells from metastatic castration-resistant prostate cancer patients

GSE38043

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We analyzed the global gene expression pattern of Tregs between healthy donors and prostate cancer patients. We found that genes related to cell cycle, cellular proliferation, immune responses, hematological system development and function were differentially expressed in Tregs from prostate cancer patients.

PubMed ID

23319273

Publication Title

Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

Total Samples

Submitter’s Institution

National Institutes of Health

Authors

Huen NY, Pang AL, Tucker JA, Lee TL, Vergati M, Jochems C, Intrivici C, Cereda V, Chan WY, Rennert OM, Madan RA, Gulley JL, Schlom J, Tsang KY

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-38043

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