Tobacco smoke exposure-related pathway gene expression signature in the bronchial airway epithelium

GSE37058

Homo sapiens

51 Downloadable Samples

Affymetrix Human Human Exon 1.0 ST Array (huex10st), Affymetrix Human Exon 1.0 ST Array [CDF: Brainarray Version 11.0.1, HuEx10stv2_Hs_ENTREZG (huex10st)

Submitter Supplied Information

Description

Using primary human bronchial epithelial cells collected at bronchoscopy, we have perturbed signaling pathways important in regulation of response to tobacco smoke exposure and cancer development: ATM, BCL2, GPX1, NOS2, IKBKB, and SIRT1

PubMed ID

22986747

Publication Title

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue.

Total Samples

Submitter’s Institution

Boston University Medical Center

Authors

Beane J, Cheng L, Soldi R, Zhang X, Liu G, Anderlind C, Lenburg ME, Spira A, Bild AH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-37058

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