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Accession IconGSE36019

Gene expression profiles in lymph nodes from ferrets infected with A/California/07/2009

Organism Icon Mustela putorius furo
Sample Icon 15 Downloadable Samples
Technology Badge Icon Affymetrix Canine Genome 2.0 Array (canine2)

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Description
Pandemic H1N1 influenza A Human infection leads to symptoms ranging from mild to severe with lower respiratory complications observed in a small but significant number of infected individuals. Microarray analysis of the lymph nodes from ferrets infected with A/California/07/2009 shows intense gene upregulation during days 3 and 5 post-infection, and followed by marked downregulation during days 7 and 14 post infection. Gene expression profiles during the upregulation phase show intense chemokine activity, cell replication and activation of the lymphocyte-related signaling pathways.
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