Expression data of Xrx1 gain and loss of function experiments from early Xenopus laevis embryos (stage 13)

Eye development is a multistep process that requires specific inductive signals and precise morphogenetic movements, starting early during development in the eye-field, a well-definite region of the anterior neural plate. It has been demonstrated that a gene network of eye field transcription factors (EFTFs) contributes to specify the neural and retinal fate of the eye field. Among these EFTFs, Xrx1 is involved in proliferation and neurogenesis in the eye field and is necessary for the correct development of the retina.

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Giannaccini M, Giudetti G, Biasci D, Mariotti S, Martini D, Barsacchi G, Andreazzoli M